Near-infrared persistent luminescence (PersL) nanoparticles (NPs) have great potential in biomedical applications due to their ability to continuously emit tissue-penetrating light.Despite numerous reports on the distribution, biological safety and other consequences of PersL NPs in vitro and in vivo, there has been a lack of studies on the optical properties of these NPs in the physiological environment.In Picture Frame Light Box light of this, we investigated the effects of short-term immersion of the prominent Cr3+-doped ZnGa2O4 (CZGO) NPs in a simulated physiological environment for up to 48 h.
This paper reports the changes in the structural and optical properties of CZGO NPs after their immersion in a phosphate-buffered saline (PBS) solution for Range Hood pre-determined time intervals.Interestingly, the luminescence intensity and lifetime noticeably improved upon exposure to the PBS media, which is unusual among existing nanomaterials explored as bioimaging probes.After 48 h of immersion in the PBS solution, the CZGO NPs were approximately twice as bright as the non-immersed sample.
X-ray spectroscopic techniques revealed the formation of ZnO, which results in an improvement in observed luminescence.